This page covers IGF-1 LR3, the modified form of insulin-like growth factor 1 that we carry as a research material. Anyone searching for igf 1 or for the igf hormone lands on a family of closely related molecules, so this page says which member Lumo Peptides lists and what it costs. Below are the pack and price, the chemistry, the neighbouring compounds, notes on form and storage, and how an order reaches the United Kingdom or Ireland.
Everything here is meant for laboratory and research work. IGF-1 LR3 is not sold by us as a medicine, a supplement or a cosmetic, and we make no claim about what anyone would observe. What we describe is the chemistry and the logistics. Each batch is analysed and the certificate of analysis is published in the laboratory analysis reports.
Price and packaging
| Product | Pack | Price | Price per mg |
|---|---|---|---|
| IGF-1 LR3 | 1 mg lyophilised vial | € 104,95 | € 104,95 |
This line has one pack size, so the per-milligram figure follows straight from the vial price: one vial holds one milligram, which puts the material at € 104,95 per mg. There is no larger pack to weigh it against. Where a Lumo line does come in several sizes, we work the figure out per row: the biggest vial is not always cheaper per milligram.
What IGF-1 LR3 is
IGF-1 LR3 is short for Long R3 insulin-like growth factor 1. The parent molecule appears in older literature as somatomedin C. It is a single-chain polypeptide of 70 amino acids whose fold is closely related to that of proinsulin, held in shape by three intramolecular disulfide bridges. That kinship with insulin is where the name comes from.
The LR3 variant carries two deliberate changes to that sequence. A 13-amino-acid extension is added at the N-terminus, and the glutamate at position 3 is swapped for an arginine, the R3 in the name. The chain runs to 83 amino acids in total, with a molecular mass of roughly 9,100 g/mol. That is large for a catalogue peptide, and it is why this line is vialled at one milligram.
Published work describes those two modifications as altering how the molecule associates with the IGF-binding proteins that ordinarily accompany native IGF-1 in solution. That is a point of protein chemistry, not a claim about any outcome.
Where it sits in the catalogue
The nearest relative in our catalogue comes from the same gene. PEG-MGF is the polyethylene-glycol-modified form of mechano growth factor, itself a splice variant of the IGF-1 gene, so it shares part of its sequence while differing at the C-terminus. Further upstream sits HGH, a 191-amino-acid protein and a larger molecule again; that whole group is set out on our buy HGH page.
Further off are the peptide analogues that arrive at the same research area by another chemical route, such as CJC-1295 with ipamorelin. Those are far smaller molecules. Comparing price per milligram across such different masses says little; it only carries meaning within one group. The full catalogue index is on buy peptides.
Form, handling and storage
IGF-1 LR3 is supplied as a lyophilised cake in a sealed glass vial. To reconstitute it, run the bacteriostatic water slowly down the inner wall of the vial rather than jetting it onto the cake, then swirl gently until the solid has dissolved. Do not shake. On a 1 mg vial the volume of solvent sets the final concentration, and a small difference moves that figure a long way, so measure it.
An unopened vial keeps dry and dark. Once reconstituted, the material belongs in the fridge rather than the freezer, since repeated freezing and thawing is hard on a protein of this size. Other lines come as tablets, kept dry and dark in the blister, or as a nasal kit holding the vial, an empty spray bottle and the solvent. Neither applies here; this line is a vial only.
Shipping and analysis
Everything ships from the Netherlands. Delivery to the United Kingdom is a flat € 15,95 and free from € 200; delivery to Ireland is a flat € 14,95, likewise free from € 200. All prices on the site are in euros. The United Kingdom is not in the EU, so a parcel to a British address is an import: any import VAT or duty that falls due is charged by the carrier to the recipient. Ireland is in the EU, so no such import charges arise there.
Every batch is analysed and a certificate of analysis is available. We quote the measured figure from that report, not a number carried over from the previous batch.
Frequently asked questions
What does LR3 stand for?
Long R3. Long refers to the 13-amino-acid extension at the N-terminus, R3 to the arginine at position 3 in place of the glutamate of native IGF-1.
What may I use this for?
Laboratory and research purposes only. It is not for human or veterinary use, and we give no instructions for use of any kind.
How does IGF-1 LR3 differ from IGF-1 itself?
By those two structural changes, and by chain length: 83 amino acids against 70.
Is the 1 mg vial the only pack for this line?
The catalogue lists one pack, a 1 mg lyophilised vial at € 104,95. The product page carries the current listing.
Will anything be charged on delivery in the United Kingdom?
Possibly. A parcel from the Netherlands to a UK address is an import, and the carrier collects any import VAT or duty from the recipient. For Ireland this does not apply.
For laboratory and research use only. Not for human or veterinary use.
